The latest health news, scientific trends and medical information
General

Heparin-Induced Thrombocytopenia

Heparin-induced thrombocytopenia (HIT) is a complication of heparin therapy. [1]There are two types of HIT. Type 1 HIT presents within the first 2 days after exposure to heparin, and the platelet count normalizes with continued heparin therapy. Type 1 HIT is a nonimmune disorder that results from the direct effect of …

Read More
General

Acquired Hemophilia

Acquired hemophilia is a rare but potentially life-threatening bleeding disorder caused by the development of autoantibodies (inhibitors) directed against plasma coagulation factors, most frequently factor VIII (FVIII). Signs and symptoms Most patients with acquired hemophilia present with hemorrhages into the skin, muscles, or soft tissues and mucous membranes. Intra-articular bleeding …

Read More
General

Angina Pectoris in Emergency Medicine

Angina pectoris (AP) represents the clinical syndrome occurring when myocardial oxygen demand exceeds supply. The term is derived from Latin; the literal meaning is “the choking of the chest;” angere, meaning “to choke” and pectus, meaning “chest.” The first English-written account of recurrent angina pectoris was by English nobleman Edward Hyde, Earl of Clarendon. He …

Read More
General

Anticoagulation in Deep Venous Thrombosis

Anticoagulant therapy remains the mainstay of medical therapy for deep venous thrombosis (DVT) because it is noninvasive, it treats most patients (approximately 90%) with no immediate demonstrable physical sequelae of DVT, it has a low risk of complications, and its outcome data demonstrate an improvement in morbidity and mortality. Meta-analyses …

Read More
General

Acute Pericarditis

Practice Essentials Acute pericarditis is an inflammation of the pericardium characterized by chest pain, pericardial friction rub, and serial ECG changes. The first and last stages of ECG changes are seen in the images below. Stage 1 electrocardiograph changes in a patient with acute pericarditis. View Media Gallery Stage 4 …

Read More
General

Acute Aortic Dissection

Aortic dissection is the most common catastrophe of the aorta, 2-3 times more common than rupture of the abdominal aorta. When left untreated, about 33% of patients die within the first 24 hours, and 50% die within 48 hours. The 2-week mortality rate approaches 75% in patients with undiagnosed ascending …

Read More
General

Acute Angioedema

The goals of emergency treatment of angioedema are to prevent spontaneous eruption, to maintain a patent airway if eruption does occur, and to stop progression of disease. [1] Laryngeal edema may occur rapidly. In these cases, a definitive airway such as an endotracheal tube should be established. If the airway cannot be …

Read More
General

Immunoglobulin A Deficiency

Selective immunoglobulin A deficiency (SIgAD) is a primary immunodeficiency disease and is the most common of the primary antibody deficiencies. [1] Total immunoglobulin A deficiency (IgAD) is defined as an undetectable serum immunoglobulin A (IgA) level at a value < 5 mg/dL (0.05 g/L) in humans. Partial IgAD refers to detectable but …

Read More
General

Hypogammaglobulinemia

Hypogammaglobulinemia refers to a set of clinicolaboratory entities with varied causes and manifestations. The common clinical feature of hypogammaglobulinemia relates to a predisposition toward infections that normally are defended against by antibody responses (including Streptococcus pneumoniaeand Haemophilus influenzae infections). Signs and symptoms Most patients with hypogammaglobulinemia present with a history of recurrent infections. …

Read More
General

NEW CEMENT-LIKE MATERIAL CAN REPAIR HIP DAMAGE

Each year, more than 300,000 Americans receive a hip replacement. It’s a major surgery that requires months of physical rehabilitation, and there’s no guarantee the implant will last forever, especially in younger patients. But doctors at The Ohio State Wexner Medical Center are giving patients new options that allow them to repair their …

Read More
Show Buttons
Hide Buttons